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Preeclampsia is predictable


Some mothers tend to have sudden blood pressure surges during pregnancy, which is a leading symptom of preeclampsia. Knowledge A new, state-of-the-art method has been developed for early warning of illness in early pregnancy.

The new method is based on a "metabolite profile": it detects metabolic products in the blood that are predictive of disease. There are 14 molecules that are biomarker molecules, thus indicating whether the disease develops in the later stages of pregnancy or not. An international research group published a paper on this in the October issue of Hypertension. "Preeclampsia usually develops only in the third trimester of pregnancy. Professor of Obstetrics and Gynecology at the Anu Research Center in University College, Cork. "In order to prevent and treat the disease properly, we need to start treatment early in the pregnancy, recognizing the high risk of developing the disease."
Preeclampsia can be a life-threatening disease, the main symptom of which is the appearance of white in the urine from the blood pressure protrusions. Pregnancy rates are 5 percent higher but the cause of maternal mortality is worldwide. It should be taken seriously as it not only threatens to cause blood pressure jumps but can also cause seizures similar to epilepsy. We cannot treat the disease, the only option is to have a baby at birth - even in early pregnancy, they recommend it. Earlyborns have a much higher incidence of illness and mortality.
Although the exact causes of the disease are unknown, the source of the disorder is early onset of the bed and its symptoms only occur in the second half of the pregnancy. In the experiment, 7,000 first-time pregnant mothers were tested. Sixty-first pregnant healthy mothers were selected and had a low risk of preeclampsia and showed signs of illness in late pregnancy.
The mid-30s were white-skinned and were from New Zealand. Pregnant We completed the required blood test at week 15. All 14 biomarkers were positive. Researchers have also tried the method in Austria - younger and more ethnically diverse in young mothers. 39 out of 40 babies have all 14 biomarkers in early pregnancy.
The results allow for timely diagnosis and closer monitoring, improving the health of mothers and their fetus. Unfortunately, experiments are still at an early stage and must be performed on other populations in order to make the filtration common. To get closer to the cause of preeclampsia, they may develop new treatment schemes, which could also be a great advance. Research is continuing. Over the next year, researchers aim to develop a test method that can screen high-risk babies from the very early stages of pregnancy.